node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRHP | DBNL | ENSP00000455329 | ENSP00000417653 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | drebrin-like; Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G- actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse [...] | 0.434 |
CRHP | LMO1 | ENSP00000455329 | ENSP00000338207 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors | 0.609 |
CRHP | LMO2 | ENSP00000455329 | ENSP00000257818 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | 0.482 |
CRHP | LMO3 | ENSP00000455329 | ENSP00000312856 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | LIM domain only 3 (rhombotin-like 2) | 0.745 |
CRHP | POTEE | ENSP00000455329 | ENSP00000439189 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | POTE ankyrin domain family member E | 0.422 |
CRHP | POTEF | ENSP00000455329 | ENSP00000350052 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | POTE ankyrin domain family, member F | 0.422 |
CRHP | POTEI | ENSP00000455329 | ENSP00000392718 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | POTE ankyrin domain family, member I | 0.422 |
CRHP | POTEJ | ENSP00000455329 | ENSP00000387176 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | POTE ankyrin domain family, member J | 0.422 |
CRHP | PRL | ENSP00000455329 | ENSP00000302150 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | prolactin; Prolactin acts primarily on the mammary gland by promoting lactation | 0.440 |
CRHP | SPARC | ENSP00000455329 | ENSP00000231061 | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | secreted protein, acidic, cysteine-rich (osteonectin); Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity | 0.518 |
DBNL | CRHP | ENSP00000417653 | ENSP00000455329 | drebrin-like; Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G- actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse [...] | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | 0.434 |
DBNL | POTEE | ENSP00000417653 | ENSP00000439189 | drebrin-like; Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G- actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse [...] | POTE ankyrin domain family member E | 0.715 |
DBNL | POTEF | ENSP00000417653 | ENSP00000350052 | drebrin-like; Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G- actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse [...] | POTE ankyrin domain family, member F | 0.722 |
DBNL | POTEI | ENSP00000417653 | ENSP00000392718 | drebrin-like; Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G- actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse [...] | POTE ankyrin domain family, member I | 0.715 |
DBNL | POTEJ | ENSP00000417653 | ENSP00000387176 | drebrin-like; Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G- actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse [...] | POTE ankyrin domain family, member J | 0.715 |
LMO1 | CRHP | ENSP00000338207 | ENSP00000455329 | LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | 0.609 |
LMO1 | SPARC | ENSP00000338207 | ENSP00000231061 | LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors | secreted protein, acidic, cysteine-rich (osteonectin); Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity | 0.462 |
LMO2 | CRHP | ENSP00000257818 | ENSP00000455329 | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | 0.482 |
LMO3 | CRHP | ENSP00000312856 | ENSP00000455329 | LIM domain only 3 (rhombotin-like 2) | cysteine-rich protein 1 (intestinal); Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein | 0.745 |
LMO3 | SPARC | ENSP00000312856 | ENSP00000231061 | LIM domain only 3 (rhombotin-like 2) | secreted protein, acidic, cysteine-rich (osteonectin); Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity | 0.401 |