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STRINGSTRING
TTBK1 TTBK1 ZNF610 ZNF610 GNG10 GNG10 PCDHGA4 PCDHGA4 OR7G2 OR7G2 FAM150A FAM150A TTBK2 TTBK2 SZT2 SZT2 ZNF683 ZNF683
"PCDHGA4" - protocadherin gamma subfamily A, 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
PCDHGA4protocadherin gamma subfamily A, 4; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (931 aa)    
Predicted Functional Partners:
OR7G2
olfactory receptor, family 7, subfamily G, member 2; Odorant receptor (Potential) (345 aa)
            score_image   0.563
ZNF683
zinc finger protein 683; May be involved in transcriptional regulation (504 aa)
            score_image   0.562
TTBK2
tau tubulin kinase 2; Serine/threonine kinase that acts as a key regulator of ciliogenesis- controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro (1244 aa)
            score_image   0.519
FAM150A
family with sequence similarity 150, member A (129 aa)
            score_image   0.508
ZNF610
zinc finger protein 610; May be involved in transcriptional regulation (462 aa)
            score_image   0.499
TTBK1
tau tubulin kinase 1; Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU (1321 aa)
            score_image   0.489
GNG10
guanine nucleotide binding protein (G protein), gamma 10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3 (68 aa)
            score_image   0.487
SZT2
seizure threshold 2 homolog (mouse) (3375 aa)
            score_image   0.407
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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