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CRLF3 CRLF3 LRRC37B LRRC37B UTP6 UTP6 TEFM TEFM TRMT10C TRMT10C KBTBD7 KBTBD7 POLRMT POLRMT
"TEFM" - transcription elongation factor, mitochondrial in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
TEFMtranscription elongation factor, mitochondrial; Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery (360 aa)    
Predicted Functional Partners:
TRMT10C
tRNA methyltransferase 10 homolog C (S. cerevisiae); Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5’-ends (403 aa)
      score_image     score_image   0.621
KBTBD7
kelch repeat and BTB (POZ) domain containing 7 (684 aa)
        score_image       0.603
LRRC37B
leucine rich repeat containing 37B (947 aa)
            score_image   0.509
POLRMT
polymerase (RNA) mitochondrial (DNA directed); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) (1230 aa)
            score_image   0.470
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (597 aa)
            score_image   0.468
CRLF3
cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression (442 aa)
            score_image   0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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