ENSG00000266997 protein (Homo sapiens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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some 3D structure is known or predicted

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second shell of interactors

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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Predicted Interactions

gene neighborhood

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Score

ENSG00000266997

annotation not available (164 aa)

Predicted Functional Partners:

MYO9B

0.614

MYO9A

0.614

POTEE

0.536

POTEI

0.536

POTEJ

0.536

POTEF

0.536

MYO3B

0.531

MYO3A

0.531

ENSG00000266714

0.529

MYO10

0.529

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSG00000266714	ENSG00000266997	ENSP00000463645	ENSP00000467396	Putative unconventional myosin-XVB ; Unknown, due to the absence of a functional motor domain	annotation not available	0.529
ENSG00000266714	POTEE	ENSP00000463645	ENSP00000439189	Putative unconventional myosin-XVB ; Unknown, due to the absence of a functional motor domain	POTE ankyrin domain family member E	0.536
ENSG00000266714	POTEF	ENSP00000463645	ENSP00000350052	Putative unconventional myosin-XVB ; Unknown, due to the absence of a functional motor domain	POTE ankyrin domain family, member F	0.539
ENSG00000266714	POTEI	ENSP00000463645	ENSP00000392718	Putative unconventional myosin-XVB ; Unknown, due to the absence of a functional motor domain	POTE ankyrin domain family, member I	0.536
ENSG00000266714	POTEJ	ENSP00000463645	ENSP00000387176	Putative unconventional myosin-XVB ; Unknown, due to the absence of a functional motor domain	POTE ankyrin domain family, member J	0.536
ENSG00000266997	ENSG00000266714	ENSP00000467396	ENSP00000463645	annotation not available	Putative unconventional myosin-XVB ; Unknown, due to the absence of a functional motor domain	0.529
ENSG00000266997	MYO10	ENSP00000467396	ENSP00000421280	annotation not available	myosin X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podoso [...]	0.529
ENSG00000266997	MYO3A	ENSP00000467396	ENSP00000265944	annotation not available	myosin IIIA; Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing	0.531
ENSG00000266997	MYO3B	ENSP00000467396	ENSP00000386213	annotation not available	myosin IIIB	0.531
ENSG00000266997	MYO9A	ENSP00000467396	ENSP00000348349	annotation not available	myosin IXA	0.614
ENSG00000266997	MYO9B	ENSP00000467396	ENSP00000380444	annotation not available	myosin IXB; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. May be involved in the remodeling of the actin cytoskeleton. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activating protein on Rho	0.614
ENSG00000266997	POTEE	ENSP00000467396	ENSP00000439189	annotation not available	POTE ankyrin domain family member E	0.536
ENSG00000266997	POTEF	ENSP00000467396	ENSP00000350052	annotation not available	POTE ankyrin domain family, member F	0.536
ENSG00000266997	POTEI	ENSP00000467396	ENSP00000392718	annotation not available	POTE ankyrin domain family, member I	0.536
ENSG00000266997	POTEJ	ENSP00000467396	ENSP00000387176	annotation not available	POTE ankyrin domain family, member J	0.536
MYO10	ENSG00000266997	ENSP00000421280	ENSP00000467396	myosin X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podoso [...]	annotation not available	0.529
MYO10	POTEE	ENSP00000421280	ENSP00000439189	myosin X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podoso [...]	POTE ankyrin domain family member E	0.536
MYO10	POTEF	ENSP00000421280	ENSP00000350052	myosin X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podoso [...]	POTE ankyrin domain family, member F	0.543
MYO10	POTEI	ENSP00000421280	ENSP00000392718	myosin X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podoso [...]	POTE ankyrin domain family, member I	0.536
MYO10	POTEJ	ENSP00000421280	ENSP00000387176	myosin X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podoso [...]	POTE ankyrin domain family, member J	0.536

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