GIPR protein (Homo sapiens) - STRING network view

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GIPR

gastric inhibitory polypeptide receptor; This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (466 aa)

Predicted Functional Partners:

GIP

0.996

POMC

0.987

GCG

0.986

ADCY5

0.973

VIP

0.956

HTR4

0.944

ADRB1

0.943

LHCGR

0.934

MC4R

0.933

MC2R

0.928

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	ADRB1	ENSP00000419361	ENSP00000358301	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	0.921
ADCY5	GCG	ENSP00000419361	ENSP00000387662	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life	0.923
ADCY5	GIP	ENSP00000419361	ENSP00000350005	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	gastric inhibitory polypeptide; Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion	0.919
ADCY5	GIPR	ENSP00000419361	ENSP00000467494	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	gastric inhibitory polypeptide receptor; This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase	0.973
ADCY5	HTR4	ENSP00000419361	ENSP00000353915	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	0.907
ADCY5	LHCGR	ENSP00000419361	ENSP00000294954	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	luteinizing hormone/choriogonadotropin receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase	0.906
ADCY5	MC2R	ENSP00000419361	ENSP00000333821	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	melanocortin 2 receptor (adrenocorticotropic hormone); Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase	0.911
ADCY5	MC4R	ENSP00000419361	ENSP00000299766	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	melanocortin 4 receptor; Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase	0.918
ADCY5	POMC	ENSP00000419361	ENSP00000264708	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol	0.913
ADCY5	VIP	ENSP00000419361	ENSP00000356213	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	vasoactive intestinal peptide; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder	0.905
ADRB1	ADCY5	ENSP00000358301	ENSP00000419361	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase	0.921
ADRB1	GCG	ENSP00000358301	ENSP00000387662	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life	0.906
ADRB1	GIP	ENSP00000358301	ENSP00000350005	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	gastric inhibitory polypeptide; Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion	0.932
ADRB1	GIPR	ENSP00000358301	ENSP00000467494	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	gastric inhibitory polypeptide receptor; This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase	0.943
ADRB1	HTR4	ENSP00000358301	ENSP00000353915	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	0.908
ADRB1	LHCGR	ENSP00000358301	ENSP00000294954	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	luteinizing hormone/choriogonadotropin receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase	0.930
ADRB1	MC2R	ENSP00000358301	ENSP00000333821	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	melanocortin 2 receptor (adrenocorticotropic hormone); Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase	0.900
ADRB1	MC4R	ENSP00000358301	ENSP00000299766	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	melanocortin 4 receptor; Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase	0.902
ADRB1	POMC	ENSP00000358301	ENSP00000264708	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol	0.919
ADRB1	VIP	ENSP00000358301	ENSP00000356213	adrenoceptor beta 1; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity	vasoactive intestinal peptide; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder	0.900

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