node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC134 | FBXO18 | ENSP00000255784 | ENSP00000369335 | coiled-coil domain containing 134 | F-box protein, helicase, 18 | 0.664 |
CCDC134 | NUDCD1 | ENSP00000255784 | ENSP00000239690 | coiled-coil domain containing 134 | NudC domain containing 1 | 0.597 |
CCDC134 | TXNL4B | ENSP00000255784 | ENSP00000268483 | coiled-coil domain containing 134 | thioredoxin-like 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition | 0.636 |
CCDC134 | ZNF461 | ENSP00000255784 | ENSP00000467931 | coiled-coil domain containing 134 | zinc finger protein 461; May be involved in transcriptional regulation | 0.665 |
FBXO18 | CCDC134 | ENSP00000369335 | ENSP00000255784 | F-box protein, helicase, 18 | coiled-coil domain containing 134 | 0.664 |
FBXO18 | NUDCD1 | ENSP00000369335 | ENSP00000239690 | F-box protein, helicase, 18 | NudC domain containing 1 | 0.544 |
FBXO18 | TXNL4B | ENSP00000369335 | ENSP00000268483 | F-box protein, helicase, 18 | thioredoxin-like 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition | 0.605 |
FBXO18 | ZNF461 | ENSP00000369335 | ENSP00000467931 | F-box protein, helicase, 18 | zinc finger protein 461; May be involved in transcriptional regulation | 0.563 |
HDAC2 | NR4A1 | ENSP00000430432 | ENSP00000353427 | histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed o [...] | nuclear receptor subfamily 4, group A, member 1; Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5’- AAAAGGTCA-3’ (By similarity). May inhibit NF-kappa-B transactivation of IL2 | 0.403 |
HDAC2 | ZNF461 | ENSP00000430432 | ENSP00000467931 | histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed o [...] | zinc finger protein 461; May be involved in transcriptional regulation | 0.775 |
HEATR4 | ZNF461 | ENSP00000335447 | ENSP00000467931 | HEAT repeat containing 4 | zinc finger protein 461; May be involved in transcriptional regulation | 0.673 |
NR4A1 | HDAC2 | ENSP00000353427 | ENSP00000430432 | nuclear receptor subfamily 4, group A, member 1; Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5’- AAAAGGTCA-3’ (By similarity). May inhibit NF-kappa-B transactivation of IL2 | histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed o [...] | 0.403 |
NR4A1 | ZNF461 | ENSP00000353427 | ENSP00000467931 | nuclear receptor subfamily 4, group A, member 1; Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5’- AAAAGGTCA-3’ (By similarity). May inhibit NF-kappa-B transactivation of IL2 | zinc finger protein 461; May be involved in transcriptional regulation | 0.888 |
NUDCD1 | CCDC134 | ENSP00000239690 | ENSP00000255784 | NudC domain containing 1 | coiled-coil domain containing 134 | 0.597 |
NUDCD1 | FBXO18 | ENSP00000239690 | ENSP00000369335 | NudC domain containing 1 | F-box protein, helicase, 18 | 0.544 |
NUDCD1 | TXNL4B | ENSP00000239690 | ENSP00000268483 | NudC domain containing 1 | thioredoxin-like 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition | 0.513 |
NUDCD1 | ZNF461 | ENSP00000239690 | ENSP00000467931 | NudC domain containing 1 | zinc finger protein 461; May be involved in transcriptional regulation | 0.604 |
SF1 | ZNF461 | ENSP00000366604 | ENSP00000467931 | splicing factor 1 | zinc finger protein 461; May be involved in transcriptional regulation | 0.576 |
TOX | ZNF461 | ENSP00000354842 | ENSP00000467931 | thymocyte selection-associated high mobility group box; May play a role in regulating T-cell development (By similarity) | zinc finger protein 461; May be involved in transcriptional regulation | 0.602 |
TOX2 | ZNF461 | ENSP00000344724 | ENSP00000467931 | TOX high mobility group box family member 2; Putative transcriptional activator involved in the hypothalamo-pituitary-gonadal system | zinc finger protein 461; May be involved in transcriptional regulation | 0.955 |