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STRINGSTRING
TCF3 TCF3 TCF12 TCF12 TCF4 TCF4 ASCL5 ASCL5 ZNF837 ZNF837 ARMCX4 ARMCX4 CCDC13 CCDC13
"ASCL5" - achaete-scute complex homolog 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASCL5achaete-scute complex homolog 5 (Drosophila) (278 aa)    
Predicted Functional Partners:
ARMCX4
armadillo repeat containing, X-linked 4 (2290 aa)
            score_image   0.591
ZNF837
zinc finger protein 837; May be involved in transcriptional regulation (By similarity) (531 aa)
            score_image   0.581
CCDC13
coiled-coil domain containing 13 (715 aa)
            score_image   0.485
TCF4
transcription factor 4 (671 aa)
        score_image   score_image   0.468
TCF12
transcription factor 12; Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5’-CANNTG-3’) (706 aa)
        score_image   score_image   0.468
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue- specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E- box motifs- 5’-CANNTG-3’. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region (654 aa)
        score_image   score_image   0.468
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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