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LSM1 LSM1 LSM3 LSM3 NAA38 NAA38 LSM5 LSM5 PRPF4 PRPF4 LSM6 LSM6 LSM7 LSM7 GRP GRP PATL1 PATL1 LSM4 LSM4 SART3 SART3
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
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co-expression
homology edge
protein homology
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[Homology]
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LSM4LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA (139 aa)    
Predicted Functional Partners:
LSM7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA and is probably a component of the spliceosome (103 aa)
      score_image score_image score_image score_image   0.999
LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA (102 aa)
      score_image score_image score_image score_image   0.999
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae); Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5’-to-3’ mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing [...] (80 aa)
      score_image score_image score_image score_image   0.999
LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA (133 aa)
      score_image score_image score_image score_image   0.999
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit; Binds specifically to the 3’-terminal U-tract of U6 snRNA and is probably a component of the spliceosome (96 aa)
      score_image score_image   score_image   0.999
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in U6 snRNP assembly and function. Binds to the 3’ end of U6 snRNA, thereby facilitating formation of the spliceosomal U4/U6 duplex formation in vitro (91 aa)
      score_image score_image score_image score_image   0.999
SART3
squamous cell carcinoma antigen recognized by T cells 3; Regulates Tat transactivation activity through direct interaction. May be a cellular factor for HIV-1 gene expression and viral replication (963 aa)
        score_image   score_image   0.999
GRP
gastrin-releasing peptide; GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP- receptor gene expression, long-term potentiation, and amygdala- dependent memory for fear (By similarity) (148 aa)
        score_image   score_image   0.999
PATL1
protein associated with topoisomerase II homolog 1 (yeast); RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV) (770 aa)
        score_image score_image score_image   0.995
PRPF4
PRP4 pre-mRNA processing factor 4 homolog (yeast); Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (522 aa)
        score_image   score_image   0.994
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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