Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
PGK1 PGK1 ENO1 ENO1 PKLR PKLR PNMAL2 PNMAL2 ENSG00000266953 ENSG00000266953 ENO4 ENO4 ENO3 ENO3 TPI1 TPI1 PKM PKM ENO2 ENO2 PGK2 PGK2
"PNMAL2" - paraneoplastic Ma antigen family-like 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNMAL2paraneoplastic Ma antigen family-like 2 (635 aa)    
Predicted Functional Partners:
PGK1
phosphoglycerate kinase 1; In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) (417 aa)
score_image     score_image score_image   score_image   0.942
PGK2
phosphoglycerate kinase 2 (417 aa)
score_image     score_image score_image   score_image   0.942
ENO4
enolase family member 4 (628 aa)
score_image     score_image score_image   score_image   0.941
ENO3
enolase 3 (beta, muscle); Appears to have a function in striated muscle development and regeneration (434 aa)
score_image     score_image score_image   score_image   0.941
ENO1
enolase 1, (alpha) (434 aa)
score_image     score_image score_image   score_image   0.941
ENO2
enolase 2 (gamma, neuronal); Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity) (434 aa)
score_image     score_image score_image   score_image   0.941
TPI1
triosephosphate isomerase 1 (286 aa)
score_image     score_image     score_image   0.869
PKLR
pyruvate kinase, liver and RBC; Plays a key role in glycolysis (By similarity) (574 aa)
score_image     score_image     score_image   0.691
PKM
pyruvate kinase, muscle (531 aa)
score_image     score_image     score_image   0.691
ENSG00000266953
Uncharacterized protein (209 aa)
score_image     score_image     score_image   0.689
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (53%)