STRING 9.05 
PLAU [ENSP00000361850]
 
plasminogen activator, urokinase; Specifically cleave the zymogen plasminogen to form the active enzyme plasmin
SERPINE1 [ENSP00000223095]
 
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:   yes (score 0.225).  
Experimental/Biochemical Data:   yes (score 0.993).  
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.964).  
Combined Score:
 
0.999
 
Evidence for specific actions:
Binding:yes (score: 0.999)  
Catalysis:yes (score: 0.900)  
Activation:yes (score: 0.800)  
Reaction:yes (score: 0.900)