STRING 9.05 
TCF3 [ENSP00000262965]
 
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer
HAND1 [ENSP00000231121]
 
heart and neural crest derivatives expressed 1; Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'- NRTCTG-3' (non-canonical E-box) (By similarity)
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.620). In addition, putative homologs were found interacting in other species (score 0.145).  
Association in Curated Databases:  
none / insignificant.
    
Co-Mentioned in PubMed Abstracts:  
none / insignificant.
    
Combined Score:
 
0.653