STRING 9.05 
CH25H [ENSP00000360918]
cholesterol 25-hydroxylase; Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25- hydroxycholesterol by macrophages may play a role in Leydig cell differentiation
CYP46A1 [ENSP00000261835]
cytochrome P450, family 46, subfamily A, polypeptide 1; Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
Gene Fusions:  
none / insignificant.
Cooccurence Across Genomes:  
none / insignificant.
none / insignificant.
Experimental/Biochemical Data:  
none / insignificant.
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.562).  
Combined Score: