STRING 9.05 
NEDD4 [ENSP00000345530]
 
neural precursor cell expressed, developmentally down-regulated 4; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates the tumor suppressor PTEN and thus targets PTEN for proteasomal degradation. Regulates tumorigenesis in a PTEN- dependent manner. Involved in the budding of many viruses
SLC12A3 [ENSP00000262502]
 
solute carrier family 12 (sodium/chloride transporters), member 3; Electrically silent transporter system. Mediates sodium and chloride reabsorption
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.621).  
Association in Curated Databases:  
none / insignificant.
    
Co-Mentioned in PubMed Abstracts:   yes (score 0.102).  
Combined Score:
 
0.636
 
Evidence for specific actions:
Binding:yes (score: 0.621)