STRING 9.05 
BRCA1 [ENSP00000350283]
 
breast cancer 1, early onset; The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Plays a central role in DNA repair by facilitating cellular response to DNA repair. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional regulation of P21 in response to DNA damage [...]
RAD51 [ENSP00000267868]
 
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae); May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:   yes (score 0.674). In addition, putative homologs are coexpressed in other species (score 0.199).  
Experimental/Biochemical Data:   yes (score 0.974).  
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.840).  
Combined Score:
 
0.999
 
Evidence for specific actions:
Catalysis:yes (score: 0.900)  
Binding:yes (score: 0.997)  
Reaction:yes (score: 0.900)