STRING 9.05 
GSK3B [ENSP00000324806]
 
glycogen synthase kinase 3 beta; Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin
AKT1 [ENSP00000270202]
 
v-akt murine thymoma viral oncogene homolog 1; General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protei [...]
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.995).  
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.946).  
Combined Score:
 
0.999
 
Note: the two proteins have some sequence similarity (85.6 bits over 284 amino acids. click here to see the alignment).
Evidence for specific actions:
Binding:yes (score: 0.621)  
Post-translational modification:yes (score: 0.800)