STRING 9.05 
KIT [ENSP00000288135]
 
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)
PIK3R1 [ENSP00000274335]
 
phosphoinositide-3-kinase, regulatory subunit 1 (alpha); Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.991).  
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.248).  
Combined Score:
 
0.999
 
Evidence for specific actions:
Binding:yes (score: 0.999)  
Reaction:yes (score: 0.900)