STRING 9.05 
INSR [ENSP00000303830]
 
insulin receptor; This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. Mediates the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When present in a hybrid receptor with IGF1R, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a hig [...]
STAT5B [ENSP00000293328]
 
signal transducer and activator of transcription 5B; Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.846).  
Association in Curated Databases:  
none / insignificant.
    
Co-Mentioned in PubMed Abstracts:   yes (score 0.878).  
Combined Score:
 
0.980
 
Evidence for specific actions:
Post-translational modification:yes (score: 0.800)  
Binding:yes (score: 0.846)