STRING 9.05 
CHRNE [ENSP00000293780]
 
cholinergic receptor, nicotinic, epsilon; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane
CHRNA1 [ENSP00000261007]
 
cholinergic receptor, nicotinic, alpha 1 (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.621).  
Association in Curated Databases:   yes (score 0.540).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.623).  
Combined Score:
 
0.829
 
Note: the two proteins have some sequence similarity (295.4 bits over 470 amino acids. click here to see the alignment).
Evidence for specific actions:
Binding:yes (score: 0.825)