STRING 9.05 
POT1 [ENSP00000350249]
 
POT1 protection of telomeres 1 homolog (S. pombe); Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. Is a component of the double-stranded telomeric DNA- binding TRF1 complex which is involved in the regulation of telomere length by cis-inhibition of telomerase. Also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus. Component of the shelterin complex (te [...]
TPP1 [ENSP00000299427]
 
tripeptidyl peptidase I; Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity)
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.909). In addition, putative homologs were found interacting in other species (score 0.212).  
Association in Curated Databases:  
none / insignificant.
    
Co-Mentioned in PubMed Abstracts:   none, but putative homologs are mentioned together in other species (score 0.362).  
Combined Score:
 
0.948
 
Evidence for specific actions:
Binding:yes (score: 0.914)