STRING 9.05 
NOD2 [ENSP00000300589]
 
nucleotide-binding oligomerization domain containing 2; Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK- gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)
RIPK2 [ENSP00000220751]
 
receptor-interacting serine-threonine kinase 2; Activates pro-caspase-1 and pro-caspase-8. Potentiates CASP8-mediated apoptosis. Activates NF-kappa-B
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.989). In addition, putative homologs were found interacting in other species (score 0.278).  
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.947).  
Combined Score:
 
0.999
 
Evidence for specific actions:
Binding:yes (score: 0.999)