STRING 9.05 
HDAC6 [ENSP00000334061]
 
histone deacetylase 6; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin
CYLD [ENSP00000308928]
 
cylindromatosis (turban tumor syndrome); Negative regulator of TRAF2 and NF-kappa-B signaling pathway. Has deubiquitinating activity that is directed towards non-'Lys-48'-linked polyubiquitin chains. The inhibition of NF- kappa-B activation is mediated at least in part, by the deubiquitination and inactivation of TRAF2 and, to a lesser extent, TRAF6
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.619). In addition, putative homologs were found interacting in other species (score 0.332).  
Association in Curated Databases:  
none / insignificant.
    
Co-Mentioned in PubMed Abstracts:   yes (score 0.088).  
Combined Score:
 
0.735
 
Evidence for specific actions:
Binding:yes (score: 0.762)