STRING 9.05 
C10orf2 [ENSP00000309595]
 
Twinkle protein, mitochondrial Precursor (EC 3.6.1.-)(T7 gp4-like protein with intramitochondrial nucleoid localization)(T7-like mitochondrial DNA helicase)(Progressive external ophthalmoplegia 1 protein); Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as template to synthesize single-stranded DNA (ssDNA) molecules. May be a [...]
ICT1 [ENSP00000301585]
 
immature colon carcinoma transcript 1
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.417).  
Association in Curated Databases:  
none / insignificant.
    
Co-Mentioned in PubMed Abstracts:   none, but putative homologs are mentioned together in other species (score 0.124).  
Combined Score:
 
0.454
 
Evidence for specific actions:
Binding:yes (score: 0.417)