STRING 9.05 
SMAD3 [ENSP00000332973]
 
SMAD family member 3; Transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinase. SMAD3 is a receptor-regulated SMAD (R-SMAD) (By similarity)
SMAD2 [ENSP00000262160]
 
SMAD family member 2; Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.970).  
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.840). In addition, putative homologs are mentioned together in other species (score 0.074).  
Combined Score:
 
0.996
 
Note: the two proteins have some sequence similarity (938.2 bits over 424 amino acids. click here to see the alignment).
Evidence for specific actions:
Binding:yes (score: 0.993)