STRING 9.05 
IGF2 [ENSP00000338297]
 
insulin-like growth factor 2 (somatomedin A); The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development
IGFBP5 [ENSP00000233813]
 
insulin-like growth factor binding protein 5; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.620).  
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.506). In addition, putative homologs are mentioned together in other species (score 0.084).  
Combined Score:
 
0.979
 
Evidence for specific actions:
Binding:yes (score: 0.965)  
Catalysis:yes (score: 0.900)  
Reaction:yes (score: 0.900)