| OTX2 [ENSP00000343819]|
orthodenticle homeobox 2; Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'
|↔|| MITF [ENSP00000295600]|
microphthalmia-associated transcription factor; Transcription factor for tyrosinase and tyrosinase- related protein 1. Binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') found in the tyrosinase promoter. Plays a critical role in the differentiation of various cell types as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium