STRING 9.05 
FKBP1B [ENSP00000370373]
 
FK506 binding protein 1B, 12.6 kDa; Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RYR2 [ENSP00000355533]
 
ryanodine receptor 2 (cardiac); Communication between transverse-tubules and sarcoplasmic reticulum. Contraction of cardiac muscle is triggered by release of calcium ions from SR following depolarization of T- tubules (By similarity)
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.846).  
Association in Curated Databases:   yes (score 0.720).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.778). In addition, putative homologs are mentioned together in other species (score 0.067).  
Combined Score:
 
0.989
 
Evidence for specific actions:
Binding:yes (score: 0.960)