STRING 9.05 
PTGS2 [ENSP00000356438]
 
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity
TP53 [ENSP00000269305]
 
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:  
none / insignificant.
    
Experimental/Biochemical Data:   yes (score 0.621).  
Association in Curated Databases:  
none / insignificant.
    
Co-Mentioned in PubMed Abstracts:   yes (score 0.917).  
Combined Score:
 
0.966
 
Evidence for specific actions:
Expression with Inhibition:yes (score: 0.800)  
Binding:yes (score: 0.924)  
Activation:yes (score: 0.800)