STRING 9.05 
SPTA1 [ENSP00000357130]
spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane
SPTBN1 [ENSP00000349259]
spectrin, beta, non-erythrocytic 1; Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
Gene Fusions:  
none / insignificant.
Cooccurence Across Genomes:  
none / insignificant.
none / insignificant.
Experimental/Biochemical Data:   yes (score 0.619).  
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.204).  
Combined Score:
Note: the two proteins have some sequence similarity (731.1 bits over 1381 amino acids. click here to see the alignment).
Evidence for specific actions:
Binding:yes (score: 0.900)  
Reaction:yes (score: 0.900)