STRING 9.05 
MECP2 [ENSP00000395535]
 
methyl CpG binding protein 2 (Rett syndrome); Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A
CDKL5 [ENSP00000369325]
 
cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2
Evidence suggesting a functional link:
Neighborhood in the Genome:  
none / insignificant.
    
Gene Fusions:  
none / insignificant.
    
Cooccurence Across Genomes:  
none / insignificant.
    
Co-Expression:   yes (score 0.329).  
Experimental/Biochemical Data:   yes (score 0.621).  
Association in Curated Databases:  
none / insignificant.
    
Co-Mentioned in PubMed Abstracts:   yes (score 0.947).  
Combined Score:
 
0.984
 
Evidence for specific actions:
Post-translational modification:yes (score: 0.800)  
Binding:yes (score: 0.924)