STRING 9.05 
PDHA1 [ENSP00000394382]
 
pyruvate dehydrogenase (lipoamide) alpha 1; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3)
PDHB [ENSP00000307241]
 
pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3)
Evidence suggesting a functional link:
Neighborhood in the Genome:   None, but homologous genes are neighbors in other genomes (score 0.799).  
Gene Fusions:   yes (score 0.762).  
Cooccurence Across Genomes:   yes (score 0.525).  
Co-Expression:   yes (score 0.171). In addition, putative homologs are coexpressed in other species (score 0.413).  
Experimental/Biochemical Data:   yes (score 0.997). In addition, putative homologs were found interacting in other species (score 0.456).  
Association in Curated Databases:   yes (score 0.900).  
Co-Mentioned in PubMed Abstracts:   yes (score 0.891). In addition, putative homologs are mentioned together in other species (score 0.588).  
Combined Score:
 
0.999
 
Evidence for specific actions:
Reaction:yes (score: 0.900)  
Binding:yes (score: 0.999)