STRING 9.05 
  CX3CL1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CX3CL1
chemokine (C-X3-C motif) ligand 1; The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1 (397 aa)
(Homo sapiens)
Predicted Functional Partners:
CX3CR1
chemokine (C-X3-C motif) receptor 1; Receptor for the CX3C chemokine fractalkine and mediates b [...] (355 aa)
     0.999
TP53
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)
      0.912
CCR3
chemokine (C-C motif) receptor 3; Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin- [...] (355 aa)
      0.908
CCR2
chemokine (C-C motif) receptor 2; Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduce [...] (374 aa)
      0.902
CCR5
chemokine (C-C motif) receptor 5; Receptor for a number of inflammatory CC-chemokines including [...] (352 aa)
      0.886
CXCR3
chemokine (C-X-C motif) receptor 3; Receptor for CXCL9, CXCL10 and CXCL11 and mediates the prol [...] (415 aa)
      0.884
CCR1
chemokine (C-C motif) receptor 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP- [...] (355 aa)
      0.878
DIF
Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)( [...] (233 aa)
       0.878
CXCR4
chemokine (C-X-C motif) receptor 4; Receptor for the C-X-C chemokine CXCL12/SDF-1. Transduces a [...] (356 aa)
      0.877
CXCR6
chemokine (C-X-C motif) receptor 6; Receptor for the C-X-C chemokine CXCL16. Used as a corecept [...] (342 aa)
      0.874
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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