STRING 9.05 
  SLC22A4 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4; Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78. A key substrate of this transporter seems to be ergothioneine (ET) (551 aa)
(Homo sapiens)
Predicted Functional Partners:
RUNX1
runt-related transcription factor 1; CBF binds to the core site, 5'-PYGPYGGT-3', of a number of [...] (480 aa)
       0.927
PDZK1
PDZ domain containing 1; A scaffold protein that connects plasma membrane proteins and regulato [...] (519 aa)
      0.860
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1; Scaffold protein tha [...] (358 aa)
      0.760
DLG5
discs, large homolog 5 (Drosophila); May play a role at the plasma membrane in the maintenance [...] (1919 aa)
       0.752
PDZD3
PDZ domain containing 3; Acts as a regulatory protein that associates with GUCY2C and negativel [...] (491 aa)
      0.650
PADI4
peptidyl arginine deiminase, type IV; Catalyzes the citrullination/deimination of arginine resi [...] (663 aa)
       0.647
SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2; Scaffold protein tha [...] (337 aa)
      0.621
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II; Catalyzes the post-translational formation of 4- hy [...] (535 aa)
       0.556
FCRL3
Fc receptor-like 3 (734 aa)
       0.540
NAT9
N-acetyltransferase 9 (GCN5-related, putative) (207 aa)
       0.540
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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