STRING 9.05 
  THPO protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
THPO
thrombopoietin; Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets (353 aa)
(Homo sapiens)
Predicted Functional Partners:
MPL
myeloproliferative leukemia virus oncogene; Receptor for thrombopoietin. May represent a regula [...] (635 aa)
     0.999
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor); Transcription [...] (770 aa)
       0.901
HOXB4
homeobox B4; Sequence-specific transcription factor which is part of a developmental regulatory [...] (251 aa)
       0.886
VEGFA
vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and [...] (412 aa)
       0.884
SELP
selectin P (granule membrane protein 140kDa, antigen CD62); Ca(2+)-dependent receptor for myelo [...] (830 aa)
       0.878
KITLG
KIT ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of bo [...] (273 aa)
       0.853
CCND3
cyclin D3; Essential for the control of the cell cycle at the G1/S (start) transition. Potentia [...] (292 aa)
       0.852
MYB
v-myb myeloblastosis viral oncogene homolog (avian); Transcriptional activator; DNA-binding pro [...] (761 aa)
       0.852
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1); May be the important intermediate by which p5 [...] (164 aa)
       0.852
IGHV3-6
immunoglobulin heavy variable 3-6 pseudogene (599 aa)
       0.846
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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