STRING 9.05 
  TGM1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
TGM1
transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase); Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross- linking epidermal proteins during formation of the stratum corneum (817 aa)
(Homo sapiens)
Predicted Functional Partners:
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2); Potent tight-binding inhibitor of several G1 [...] (316 aa)
       0.850
CR1
complement component (3b/4b) receptor 1 (Knops blood group); Mediates cellular binding of parti [...] (2489 aa)
       0.804
HOXA7
homeobox A7; Sequence-specific transcription factor which is part of a developmental regulatory [...] (230 aa)
       0.800
NIPAL4
NIPA-like domain containing 4; Acts as a Mg(2+) transporter. Can also transport other divalent [...] (466 aa)
       0.792
IVL
involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia [...] (585 aa)
       0.752
LOR
loricrin; Major keratinocyte cell envelope protein (312 aa)
       0.750
RABGGTA
Rab geranylgeranyltransferase, alpha subunit; Catalyzes the transfer of a geranyl-geranyl moiet [...] (567 aa)
       0.675
FLG
filaggrin; Aggregates keratin intermediate filaments and promotes disulfide-bond formation amon [...] (4061 aa)
       0.659
HSPB1
heat shock 27kDa protein 1; Involved in stress resistance and actin organization (205 aa)
      0.656
RARRES3
retinoic acid receptor responder (tazarotene induced) 3; May be a growth regulator that mediate [...] (164 aa)
      0.654
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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