STRING 9.05 
  MIF protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor); Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti- inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is impor [...] (115 aa)
(Homo sapiens)
Predicted Functional Partners:
COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis); Probable protease subunit o [...] (334 aa)
      0.928
GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2); Facilitates [...] (430 aa)
      0.912
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) (413 aa)
      0.906
TAT
tyrosine aminotransferase (454 aa)
       0.899
IL4I1
interleukin 4 induced 1; Lysosomal L-amino-acid oxidase with highest specific activity with phe [...] (589 aa)
       0.899
HPD
4-hydroxyphenylpyruvate dioxygenase (393 aa)
       0.899
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); May play [...] (707 aa)
       0.878
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain; Plays a critical rol [...] (296 aa)
      0.831
UBC
ubiquitin C (685 aa)
     0.823
S100A8
S100 calcium binding protein A8; Calcium-binding protein. Has antimicrobial activity towards ba [...] (93 aa)
      0.784
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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