STRING 9.05 
  IL2RB protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
IL2RB
interleukin 2 receptor, beta; Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2 (551 aa)
(Homo sapiens)
Predicted Functional Partners:
IL2
interleukin 2; Produced by T-cells in response to antigenic or mitogenic stimulation, this prot [...] (153 aa)
     0.999
JAK1
Janus kinase 1; Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma [...] (1154 aa)
     0.999
IL2RA
interleukin 2 receptor, alpha; Receptor for interleukin-2 (272 aa)
     0.999
IL2RG
interleukin 2 receptor, gamma (severe combined immunodeficiency); Common subunit for the recept [...] (369 aa)
   0.998
IL15
interleukin 15; Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL [...] (162 aa)
     0.988
SHC1
SHC (Src homology 2 domain containing) transforming protein 1; Signaling adapter that couples a [...] (584 aa)
     0.985
LCK
lymphocyte-specific protein tyrosine kinase; Tyrosine kinase that plays an essential role for t [...] (509 aa)
    0.976
JAK2
Janus kinase 2; Plays a role in leptin signaling and control of body weight (By similarity). Ty [...] (1132 aa)
     0.971
JAK3
Janus kinase 3; Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and int [...] (1124 aa)
     0.970
STAT1
signal transducer and activator of transcription 1, 91kDa; Signal transducer and activator of t [...] (750 aa)
     0.968
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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