STRING 9.05 
  EPOR protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
EPOR
erythropoietin receptor; Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase (508 aa)
(Homo sapiens)
Predicted Functional Partners:
EPO
erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocy [...] (193 aa)
     0.999
JAK2
Janus kinase 2; Plays a role in leptin signaling and control of body weight (By similarity). Ty [...] (1132 aa)
     0.999
GRB2
growth factor receptor-bound protein 2; Adapter protein that provides a critical link between c [...] (217 aa)
     0.999
PTPN6
protein tyrosine phosphatase, non-receptor type 6; Plays a key role in hematopoiesis. This PTPa [...] (624 aa)
     0.998
PLCG1
phospholipase C, gamma 1; PLC-gamma is a major substrate for heparin-binding growth factor 1 (a [...] (1291 aa)
     0.997
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like; May mediate the transduction of intrace [...] (303 aa)
     0.995
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; Down regulates expression of stem cel [...] (512 aa)
     0.994
CISH
cytokine inducible SH2-containing protein; SOCS family proteins form part of a classical negati [...] (275 aa)
      0.994
SOCS2
suppressor of cytokine signaling 2; SOCS family proteins form part of a classical negative feed [...] (198 aa)
     0.990
SOCS3
suppressor of cytokine signaling 3; SOCS family proteins form part of a classical negative feed [...] (225 aa)
     0.990
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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