STRING 9.05 
  SERPINE1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis (402 aa)
(Homo sapiens)
Predicted Functional Partners:
plasminogen activator, urokinase; Specifically cleave the zymogen plasminogen to form the activ [...] (431 aa)
vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vi [...] (478 aa)
plasminogen activator, tissue; Converts the abundant, but inactive, zymogen plasminogen to plas [...] (562 aa)
plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a [...] (810 aa)
transforming growth factor, beta 1; Multifunctional protein that controls proliferation, differ [...] (390 aa)
SMAD family member 4; Common mediator of signal transduction by TGF-beta (transforming growth f [...] (552 aa)
albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2 [...] (609 aa)
kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an impor [...] (644 aa)
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); Functi [...] (826 aa)
epidermal growth factor (beta-urogastrone); EGF stimulates the growth of various epidermal and [...] (1207 aa)
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
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