STRING 9.05 
  PHOX2B protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PHOX2B
paired-like homeobox 2b; Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum- response element (314 aa)
(Homo sapiens)
Predicted Functional Partners:
ALK
anaplastic lymphoma receptor tyrosine kinase; Orphan receptor with a tyrosine-protein kinase ac [...] (1620 aa)
       0.884
UBC
ubiquitin C (685 aa)
      0.623
KIF1B
kinesin family member 1B; Motor for anterograde transport of mitochondria. Has a microtubule pl [...] (1770 aa)
       0.556
EDN3
endothelin 3; Endothelins are endothelium-derived vasoconstrictor peptides (238 aa)
       0.505
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase); Conversion of dopamine to noradrenalin [...] (617 aa)
       0.463
ASCL1
achaete-scute complex homolog 1 (Drosophila); May play a role at early stages of development of [...] (236 aa)
       0.461
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip); Iron-sulfur protein (IP) subunit [...] (280 aa)
       0.427
FGF19
fibroblast growth factor 19; Involved in the suppression of bile acid biosynthesis through down [...] (216 aa)
       0.400
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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