STRING 9.05 
  WFS1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
WFS1
Wolfram syndrome 1 (wolframin); Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store (890 aa)
(Homo sapiens)
Predicted Functional Partners:
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3; Phosphorylates the alpha subunit of [...] (1116 aa)
       0.868
CISD2
CDGSH iron sulfur domain 2; May play a role in calcium homeostasis (135 aa)
       0.796
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2; Binds to the 5'-UTR of the insulin-like gr [...] (599 aa)
       0.750
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1 (579 aa)
       0.750
SLC30A8
solute carrier family 30 (zinc transporter), member 8; Facilitates the accumulation of zinc fro [...] (369 aa)
       0.750
ATF6
activating transcription factor 6; Transcription factor that acts during endoplasmic reticulum [...] (670 aa)
      0.742
SYVN1
synovial apoptosis inhibitor 1, synoviolin; Acts as an E3 ubiquitin-protein ligase which accept [...] (617 aa)
      0.675
CISD1
CDGSH iron sulfur domain 1; Plays a key role in regulating maximal capacity for electron transp [...] (108 aa)
       0.675
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box); Participates in the Wnt signaling pat [...] (596 aa)
       0.659
HHEX
hematopoietically expressed homeobox; Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional [...] (270 aa)
       0.659
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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