STRING 9.05 
  PDHX protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PDHX
pyruvate dehydrogenase complex, component X; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex (501 aa)
(Homo sapiens)
Predicted Functional Partners:
DLD
dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage [...] (509 aa)
 0.999
PDHB
pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overa [...] (359 aa)
 0.999
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1; The pyruvate dehydrogenase complex catalyzes the ov [...] (390 aa)
  0.997
PDK2
pyruvate dehydrogenase kinase, isozyme 2; Inhibits the mitochondrial pyruvate dehydrogenase com [...] (407 aa)
     0.986
DLAT
dihydrolipoamide S-acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall [...] (647 aa)
  0.979
PDK3
pyruvate dehydrogenase kinase, isozyme 3; Inhibits the mitochondrial pyruvate dehydrogenase com [...] (415 aa)
      0.929
PDK4
pyruvate dehydrogenase kinase, isozyme 4; Inhibits the mitochondrial pyruvate dehydrogenase com [...] (411 aa)
      0.914
PDHA2
pyruvate dehydrogenase (lipoamide) alpha 2; The pyruvate dehydrogenase complex catalyzes the ov [...] (388 aa)
   0.905
BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide; The branched-chain alpha-keto dehy [...] (392 aa)
    0.890
LIAS
lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C [...] (372 aa)
     0.794
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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