STRING 9.05 
  CYP27B1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1; Catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D) to 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D) plays an important role in normal bone growth, calcium metabolism, and tissue differentiation (508 aa)
(Homo sapiens)
Predicted Functional Partners:
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor; Nuclear hormone receptor. Transcription factor [...] (427 aa)
      0.954
PTH
parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing [...] (115 aa)
       0.946
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1; Has a D-25-hydroxylase activity on both [...] (501 aa)
    0.934
POR
P450 (cytochrome) oxidoreductase; This enzyme is required for electron transfer from NADP to cy [...] (680 aa)
     0.905
CALCA
calcitonin-related polypeptide alpha; CGRP induces vasodilation. It dilates a variety of vessel [...] (141 aa)
       0.878
MYD88
myeloid differentiation primary response gene (88); Adapter protein involved in the Toll-like r [...] (309 aa)
      0.827
TIRAP
toll-interleukin 1 receptor (TIR) domain containing adaptor protein; Adapter involved in the TL [...] (235 aa)
       0.800
FGF23
fibroblast growth factor 23; Regulator of phosphate homeostasis. Inhibits renal tubular phospha [...] (251 aa)
       0.659
PHEX
phosphate regulating endopeptidase homolog, X-linked; Probably involved in bone and dentin mine [...] (749 aa)
       0.655
GC
group-specific component (vitamin D binding protein); Multifunctional protein found in plasma, [...] (474 aa)
       0.643
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Co-expression Experiments Databases Textmining
 
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