STRING 9.05 
  HAND1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
HAND1
heart and neural crest derivatives expressed 1; Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'- NRTCTG-3' (non-canonical E-box) (By similarity) (215 aa)
(Homo sapiens)
Predicted Functional Partners:
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25; Calcium-depende [...] (503 aa)
       0.800
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23; Calcium-depende [...] (468 aa)
       0.800
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24; Calcium-depende [...] (477 aa)
       0.798
HEY2
hairy/enhancer-of-split related with YRPW motif 2; Downstream effector of Notch signaling which [...] (337 aa)
      0.712
FHL2
four and a half LIM domains 2; May function as a molecular transmitter linking various signalin [...] (279 aa)
      0.659
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); Heterodimers betw [...] (654 aa)
       0.653
TCF12
transcription factor 12; Binds specifically to oligomers of E-box motifs. May play important ro [...] (706 aa)
       0.652
MYOD1
myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibro [...] (320 aa)
     0.651
HEYL
hairy/enhancer-of-split related with YRPW motif-like; Downstream effector of Notch signaling wh [...] (328 aa)
       0.651
HAND2
heart and neural crest derivatives expressed 2; Essential for cardiac morphogenesis, particular [...] (217 aa)
     0.650
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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