STRING 9.05 
  PROC protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PROC
protein C (inactivator of coagulation factors Va and VIIIa); Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (461 aa)
(Homo sapiens)
Predicted Functional Partners:
F5
coagulation factor V (proaccelerin, labile factor); Central regulator of hemostasis. It serves [...] (2224 aa)
     0.990
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; Inhibits a [...] (406 aa)
    0.979
F2
coagulation factor II (thrombin); Thrombin, which cleaves bonds after Arg and Lys, converts fib [...] (622 aa)
  0.977
THBD
thrombomodulin; Thrombomodulin is a specific endothelial cell receptor that forms a 1-1 stoichi [...] (575 aa)
    0.971
GGCX
gamma-glutamyl carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residue [...] (758 aa)
     0.969
PF4
platelet factor 4; Released during platelet aggregation. Neutralizes the anticoagulant effect o [...] (101 aa)
     0.964
F8
coagulation factor VIII, procoagulant component; Factor VIII, along with calcium and phospholip [...] (2351 aa)
     0.950
PROCR
protein C receptor, endothelial (EPCR); Binds activated protein C. Enhances protein C activatio [...] (238 aa)
      0.925
FURIN
furin (paired basic amino acid cleaving enzyme); Furin is likely to represent the ubiquitous en [...] (794 aa)
      0.921
F3
coagulation factor III (thromboplastin, tissue factor); Initiates blood coagulation by forming [...] (295 aa)
       0.901
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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