STRING 9.05 
  EPO protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
EPO
erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass (193 aa)
(Homo sapiens)
Predicted Functional Partners:
EPOR
erythropoietin receptor; Receptor for erythropoietin. Mediates erythropoietin- induced erythrob [...] (508 aa)
     0.999
JAK2
Janus kinase 2; Plays a role in leptin signaling and control of body weight (By similarity). Ty [...] (1132 aa)
       0.954
VEGFA
vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and [...] (412 aa)
       0.953
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); Functi [...] (826 aa)
       0.947
TFRC
transferrin receptor (p90, CD71); Cellular uptake of iron occurs via receptor-mediated endocyto [...] (760 aa)
       0.946
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor); Transcription [...] (770 aa)
       0.923
DIF
Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)( [...] (233 aa)
       0.916
GATA2
GATA binding protein 2; Transcriptional activator which regulates endothelin-1 gene expression [...] (480 aa)
       0.916
JAK1
Janus kinase 1; Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma [...] (1154 aa)
       0.906
NOS3
nitric oxide synthase 3 (endothelial cell); Produces nitric oxide (NO) which is implicated in v [...] (1203 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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