STRING 9.05 
  FUS protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
FUS
fused in sarcoma; Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity (526 aa)
(Homo sapiens)
Predicted Functional Partners:
SF3A2
splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for 'A' comp [...] (464 aa)
      0.994
SRSF2
splicing factor, arginine/serine-rich 2; Necessary for the splicing of pre-mRNA. It is required [...] (221 aa)
     0.976
PTBP1
polypyrimidine tract binding protein 1; Plays a role in pre-mRNA splicing. Binds to the polypyr [...] (557 aa)
     0.966
YBX1
Y box binding protein 1; Binds to splice sites in pre-mRNA and regulates splice site selection. [...] (324 aa)
     0.964
SRSF4
splicing factor, arginine/serine-rich 4; A probable role in alternative splice site selection d [...] (494 aa)
     0.962
SRRM1
serine/arginine repetitive matrix 1; Part of pre- and post-splicing multiprotein mRNP complexes [...] (904 aa)
    0.961
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; DNA-dependent RNA polymerase catalyze [...] (1970 aa)
      0.959
SRSF10
splicing factor, arginine/serine-rich 13A (262 aa)
      0.943
HNRNPK
microRNA 7-1; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequence [...] (464 aa)
     0.928
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1); Mediates the splicing of pre-mRNA by binding to the [...] (437 aa)
     0.926
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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