STRING 9.05 
  SERPINF1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity (418 aa)
(Homo sapiens)
Predicted Functional Partners:
VEGFA
vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and [...] (412 aa)
       0.857
PTGDS
prostaglandin D2 synthase 21kDa (brain); Catalyzes the conversion of PGH2 to PGD2, a prostaglan [...] (190 aa)
      0.709
CSNK2A1
casein kinase 2, alpha 1 polypeptide pseudogene; Casein kinases are operationally defined by th [...] (391 aa)
       0.621
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response; May participate in the obstruc [...] (504 aa)
       0.585
PRICKLE1
prickle homolog 1 (Drosophila); Necessary for nuclear localization of REST. May serve as nuclea [...] (831 aa)
       0.585
PITPNA
phosphatidylinositol transfer protein, alpha; Catalyzes the transfer of PtdIns and phosphatidyl [...] (270 aa)
       0.585
SCARF1
scavenger receptor class F, member 1; Mediates the binding and degradation of acetylated low de [...] (830 aa)
       0.571
TTR
transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstr [...] (147 aa)
      0.538
A2M
alpha-2-macroglobulin; Is able to inhibit all four classes of proteinases by a unique 'trapping [...] (1474 aa)
      0.486
YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; Ad [...] (255 aa)
       0.462
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (19%)
Permalink