STRING 9.05 
  KRAS protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
KRAS
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (189 aa)
(Homo sapiens)
Predicted Functional Partners:
RAF1
v-raf-1 murine leukemia viral oncogene homolog 1; Involved in the transduction of mitogenic sig [...] (648 aa)
     0.999
RALGDS
ral guanine nucleotide dissociation stimulator; Stimulates the dissociation of GDP from the Ras [...] (914 aa)
     0.989
SOS1
son of sevenless homolog 1 (Drosophila); Promotes the exchange of Ras-bound GDP by GTP (1333 aa)
      0.982
EGFR
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avi [...] (1210 aa)
      0.977
TP53
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)
       0.969
EGF
epidermal growth factor (beta-urogastrone); EGF stimulates the growth of various epidermal and [...] (1207 aa)
      0.953
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; This is the receptor for stem ce [...] (976 aa)
      0.951
PTPN11
protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cyt [...] (593 aa)
      0.943
RASSF2
Ras association (RalGDS/AF-6) domain family member 2; Potential tumor suppressor. Acts as a KRA [...] (326 aa)
      0.941
GRB2
growth factor receptor-bound protein 2; Adapter protein that provides a critical link between c [...] (217 aa)
      0.933
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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