STRING 9.05 
  CAMK1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CAMK1
calcium/calmodulin-dependent protein kinase I; Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes like transcriptional regulation, hormone production, translational regulation, regulation of actin filament organization and neurite outgrowth. Involved in calcium- dependent activation of the ERK pathway (By similarity). Recognizes the substrate consensus sequence [MVLIF]-x-R-x(2)-[ST]- x(3)-[MVLIF]. Phosphorylates EIF4G3/eIF4GII. In vitro phosphorylates CREB1, ATF1, CTFR, MYL9, SYN1/synapsin I [...] (370 aa)
(Homo sapiens)
Predicted Functional Partners:
SYN1
synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, an [...] (705 aa)
      0.958
CALM1
calmodulin 1 (phosphorylase kinase, delta); Calmodulin mediates the control of a large number o [...] (149 aa)
     0.887
HDAC5
histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal p [...] (1123 aa)
      0.887
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta; Calcium/calmodulin-dependent protei [...] (588 aa)
     0.874
BDNF
brain-derived neurotrophic factor; During development, promotes the survival and differentiatio [...] (329 aa)
       0.842
GRIA1
glutamate receptor, ionotropic, AMPA 1; Ionotropic glutamate receptor. L-glutamate acts as an e [...] (906 aa)
       0.831
RPS19
ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunit [...] (145 aa)
       0.802
HDAC4
histone deacetylase 4; Responsible for the deacetylation of lysine residues on the N-terminal p [...] (1084 aa)
      0.699
HDAC9
histone deacetylase 9; Responsible for the deacetylation of lysine residues on the N-terminal p [...] (1069 aa)
      0.693
ATF1
activating transcription factor 1; This protein binds the cAMP response element (CRE) (consensu [...] (271 aa)
      0.692
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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