STRING 9.05 
  ABCG5 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (651 aa)
(Homo sapiens)
Predicted Functional Partners:
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8; Transporter that appears to play an indis [...] (673 aa)
   0.988
MTTP
microsomal triglyceride transfer protein; Catalyzes the transport of triglyceride, cholesteryl [...] (894 aa)
      0.791
NPC1L1
NPC1 (Niemann-Pick disease, type C1, gene)-like 1; Play a major role in cholesterol homeostasis [...] (1359 aa)
       0.790
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1 (504 aa)
       0.752
NR1H2
nuclear receptor subfamily 1, group H, member 2; Orphan receptor. Binds preferentially to doubl [...] (460 aa)
       0.732
SREBF2
sterol regulatory element binding transcription factor 2; Transcriptional activator required fo [...] (1141 aa)
       0.722
NR1H4
nuclear receptor subfamily 1, group H, member 4; Receptor for bile acids such as chenodeoxychol [...] (472 aa)
      0.702
APOB
apolipoprotein B (including Ag(x) antigen); Apolipoprotein B is a major protein constituent of [...] (4563 aa)
      0.680
NR1H3
nuclear receptor subfamily 1, group H, member 3; Orphan receptor. Interaction with RXR shifts R [...] (447 aa)
       0.677
APOA1
apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the li [...] (267 aa)
      0.657
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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